Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.46 |
| ▸ | LIPC | P11150 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634348 | 0.90 | LIPG (0.41) | LIPGLIPCTTRIRAK4ACACB | |
| SCHEMBL13162581 | 0.87 | TTR (0.39) | LIPGLIPCTTRIRAK4 | |
| SCHEMBL15888574 | 0.87 | HCRTR1 (0.42) | LIPGLIPCKMT2AIRAK4KDM4E | |
| SCHEMBL13634332 | 0.86 | SCD5 (0.39) | TTRIRAK4ACACB | |
| SCHEMBL13634314 | 0.80 | LIPG (0.37) | LIPGLIPCKMT2AP2RY12ACACB | |
| SCHEMBL3436269 | 0.80 | HCRTR1 (0.35) | LIPGTTRKMT2AIRAK4KDM4E | |
| SCHEMBL16896321 | 0.78 | TTR (0.36) | LIPGTTRIRAK4KDM4EUSP2 | |
| SCHEMBL18207856 | 0.78 | TTR (0.36) | LIPGTTRIRAK4KDM4EUSP2 | |
| SCHEMBL13162789 | 0.78 | RIPK1 (0.36) | TTRKDM4EGSK3B | |
| SCHEMBL17383754 | 0.76 | USP2 (0.40) | KMT2AIRAK4KDM4EUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |