Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10136842 | 0.80 | HRH3 (0.49) | HRH3DPP4LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL2056291 | 0.79 | TSHR (0.51) | LMNAL3MBTL1SMN1; SMN2NPC1CHRM3 | |
| SCHEMBL3435164 | 0.77 | OGA (0.50) | HRH3LMNAL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL3549078 | 0.76 | SMN1; SMN2 (0.36) | HRH3LMNAL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL13634230 | 0.76 | HRH3 (0.55) | HRH3DPP4LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL12988798 | 0.76 | HRH3 (0.52) | HRH3DPP4LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL3559247 | 0.76 | HRH3 (0.55) | HRH3DPP4LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL29225087 | 0.76 | HRH3 (0.46) | HRH3DPP4LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL13634364 | 0.76 | HRH3 (0.46) | HRH3DPP4LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL13634292 | 0.76 | HRH3 (0.52) | HRH3DPP4LMNAL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |