Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1546958 | 0.86 | MAPK1 (0.49) | MAPK1MEN1KMT2AMAPTPKM | |
| SCHEMBL1546481 | 0.85 | HTT (0.56) | MAPK1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2771960 | 0.82 | CCR5 (0.52) | KDM4EALDH1A1DRD2LMNASIGMAR1 | |
| SCHEMBL2946817 | 0.80 | HPGD (0.45) | BLML3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL4190305 | 0.80 | KMT2A (0.61) | MAPK1MEN1KMT2AMAPTPKM | |
| SCHEMBL4190298 | 0.80 | KMT2A (0.61) | MAPK1MEN1KMT2AMAPTPKM | |
| SCHEMBL4192734 | 0.80 | KMT2A (0.61) | MAPK1MEN1KMT2AMAPTPKM | |
| SCHEMBL13634377 | 0.79 | DRD2 (0.50) | MEN1KMT2ABCHEACHEBACE1 | |
| SCHEMBL15352809 | 0.78 | MAPK1 (0.48) | BLML3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL227230 | 0.78 | MAPK1 (0.58) | L3MBTL1MAPK1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |