Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27324146 | 0.93 | DRD2 (0.58) | DRD2DRD4DRD3ACHECCR5 | |
| SCHEMBL1546767 | 0.84 | DRD2 (0.50) | DRD2ACHECCR5HDAC3HDAC4 | |
| SCHEMBL1546406 | 0.84 | MEN1 (0.56) | DRD2DRD4DRD3ACHECCR5 | |
| SCHEMBL25890035 | 0.80 | ACHE (0.60) | ACHECCR5BCHEMEN1KMT2A | |
| SCHEMBL4204428 | 0.80 | DRD2 (0.60) | DRD2DRD4ACHECCR5BCHE | |
| SCHEMBL4204422 | 0.80 | DRD2 (0.60) | DRD2DRD4ACHECCR5BCHE | |
| SCHEMBL13634368 | 0.79 | BLM (0.55) | DRD2ACHECCR5BCHEMEN1 | |
| SCHEMBL13638799 | 0.79 | DRD4 (0.52) | DRD2DRD4DRD3ACHECCR5 | |
| SCHEMBL6023725 | 0.78 | MEN1 (0.68) | DRD2ACHECCR5BCHEMEN1 | |
| SCHEMBL22755777 | 0.78 | MEN1 (0.68) | DRD2ACHECCR5BCHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |