Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740611 | 1.00 | GAA (0.35) | GAAMGAMPDK1PDK2PDK3 | |
| SCHEMBL23206546 | 1.00 | GAA (0.35) | GAAMGAMPDK1PDK2PDK3 | |
| SCHEMBL18291771 | 1.00 | GAA (0.35) | GAAMGAMPDK1PDK2PDK3 | |
| SCHEMBL25668004 | 1.00 | GAA (0.35) | GAAMGAMPDK1PDK2PDK3 | |
| SCHEMBL25551655 | 0.82 | GAA (0.34) | GAAMGAMTP53CYP3A4ALOX15 | |
| SCHEMBL23158050 | 0.82 | GAA (0.34) | GAAMGAMTP53CYP3A4ALOX15 | |
| SCHEMBL26059860 | 0.80 | PDK1 (0.36) | GAAMGAMPDK1TP53CYP3A4 | |
| SCHEMBL23178981 | 0.80 | PDK1 (0.36) | GAAMGAMPDK1TP53CYP3A4 | |
| SCHEMBL23640636 | 0.79 | GAA (0.32) | GAAMGAM | |
| SCHEMBL22349101 | 0.79 | ALDH1A1 (0.39) | GAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |