Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | DNM1L | O00429 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13270431 | 0.94 | S1PR1 (0.38) | S1PR1HDAC8HDAC6HDAC1DNM1L | |
| SCHEMBL15888674 | 0.94 | S1PR1 (0.38) | S1PR1HDAC8HDAC6HDAC1DNM1L | |
| SCHEMBL13634853 | 0.93 | HDAC8 (0.42) | S1PR1HDAC8HDAC6HDAC1DNM1L | |
| SCHEMBL13634686 | 0.87 | HDAC8 (0.47) | S1PR1HDAC8HDAC6HDAC1PIM1 | |
| SCHEMBL13164109 | 0.82 | DNM1L (0.44) | S1PR1DNM1LPIM1PDE4BIRAK4 | |
| SCHEMBL13638916 | 0.79 | HDAC8 (0.43) | S1PR1HDAC8HDAC6HDAC1 | |
| SCHEMBL13634729 | 0.79 | S1PR1 (0.45) | S1PR1HDAC8HDAC6HDAC1 | |
| SCHEMBL13634899 | 0.78 | PDE4B (0.43) | DNM1LPIM1PDE4BMCHR1KMT2A | |
| SCHEMBL13634851 | 0.78 | PDE4B (0.44) | DNM1LPIM1PDE4BMCHR1KMT2A | |
| SCHEMBL13634660 | 0.78 | IRAK4 (0.39) | DNM1LPIM1PDE4BIRAK4MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |