Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.36 |
| ▸ | GPR6 | P46095 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634863 | 0.92 | MAP3K7 (0.48) | MAP3K7SCDGPR6 | |
| SCHEMBL13634880 | 0.89 | RAB9A (0.40) | MAP3K7SCDPRSS12PIM1NPC1 | |
| SCHEMBL13634653 | 0.88 | HRH3 (0.41) | SCDGPR6CHEK1HDAC3HDAC2 | |
| SCHEMBL13634849 | 0.88 | GPR6 (0.41) | SCDGPR6CHEK1PIM1HDAC3 | |
| SCHEMBL13634547 | 0.87 | MAP3K7 (0.39) | MAP3K7SCDPRSS12GPR6PIM1 | |
| SCHEMBL13634881 | 0.87 | NPC1 (0.40) | SCDGPR6CHEK1PIM1HDAC3 | |
| SCHEMBL13634828 | 0.85 | RAB9A (0.41) | SCDPIM1NPC1MAPTRAB9A | |
| SCHEMBL13634698 | 0.83 | MAP3K7 (0.47) | MAP3K7SCDGPR6 | |
| SCHEMBL13634648 | 0.83 | MAP3K7 (0.51) | MAP3K7GPR6CHEK1LRRK2 | |
| SCHEMBL13634883 | 0.82 | NPC1 (0.43) | CHEK1PIM1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |