Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | BCL3 | P20749 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634559 | 0.95 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL13634757 | 0.93 | MAPT (0.40) | ALDH1A1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL13270599 | 0.89 | MAPT (0.41) | ALDH1A1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL13270650 | 0.88 | MAPT (0.39) | ALDH1A1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL13634573 | 0.88 | KMT2A (0.42) | ALDH1A1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL13639002 | 0.88 | KMT2A (0.42) | ALDH1A1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL2772472 | 0.85 | KMT2A (0.49) | ALDH1A1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL13634740 | 0.85 | MAPT (0.41) | ALDH1A1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL13634927 | 0.84 | CNR2 (0.36) | — | |
| SCHEMBL13634767 | 0.83 | SCD (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |