Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | BCL3 | P20749 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634573 | 0.94 | KMT2A (0.42) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL13638912 | 0.93 | KMT2A (0.47) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL13634559 | 0.93 | ALDH1A1 (0.41) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL2770504 | 0.91 | PIN1 (0.37) | KMT2AMEN1OPRK1HRH3 | |
| SCHEMBL2774531 | 0.89 | NAPEPLD (0.37) | KMT2AMEN1HRH3 | |
| SCHEMBL2770287 | 0.89 | PIN1 (0.36) | KMT2AMEN1OPRK1HRH3 | |
| SCHEMBL15888680 | 0.89 | PIN1 (0.36) | KMT2AMEN1OPRK1HRH3 | |
| SCHEMBL13164108 | 0.89 | KMT2A (0.38) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL13639003 | 0.88 | PIN1 (0.37) | KMT2AMEN1OPRK1HRH3 | |
| SCHEMBL2772472 | 0.88 | KMT2A (0.49) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |