Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | GPR6 | P46095 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638904 | 0.94 | MAP4K1 (0.39) | HRH3GPR6PIM2 | |
| SCHEMBL13634587 | 0.94 | GPR6 (0.36) | HRH3IRAK4OPRK1KMT2ASCD | |
| SCHEMBL13634843 | 0.91 | GPR6 (0.38) | IRAK4OPRK1KMT2ASCDGPR6 | |
| SCHEMBL13638779 | 0.88 | MAP4K1 (0.39) | GPR6FFAR1 | |
| SCHEMBL13638990 | 0.86 | MAP4K1 (0.38) | IRAK4GPR6KDM4EHPGD | |
| SCHEMBL13634602 | 0.85 | IDH1 (0.40) | HRH3IRAK4OPRK1KMT2A | |
| SCHEMBL13634650 | 0.85 | IRAK4 (0.50) | IRAK4OPRK1KMT2A | |
| SCHEMBL13634716 | 0.84 | HRH3 (0.40) | HRH3IRAK4OPRK1KMT2ASCD | |
| SCHEMBL13638992 | 0.82 | IRAK4 (0.39) | HRH3IRAK4OPRK1KMT2AGPR6 | |
| SCHEMBL13634719 | 0.81 | HRH3 (0.39) | HRH3IRAK4OPRK1KMT2ASCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |