Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638779 | 0.94 | MAP4K1 (0.39) | MAP4K1IDH1ADORA2AADORA1FPR1 | |
| SCHEMBL13634681 | 0.94 | HRH3 (0.38) | HRH3PIM2GPR6 | |
| SCHEMBL13638990 | 0.92 | MAP4K1 (0.38) | MAP4K1IDH1ADORA2AADORA1FPR1 | |
| SCHEMBL13634587 | 0.87 | GPR6 (0.36) | HRH3PIM2GPR6 | |
| SCHEMBL13638992 | 0.86 | IRAK4 (0.39) | IDH1HRH3SYKGPR6 | |
| SCHEMBL13634843 | 0.85 | GPR6 (0.38) | PIM2GPR6 | |
| SCHEMBL13634650 | 0.84 | IRAK4 (0.50) | — | |
| SCHEMBL13634716 | 0.83 | HRH3 (0.40) | HRH3GPR6 | |
| SCHEMBL13634602 | 0.82 | IDH1 (0.40) | IDH1HRH3 | |
| SCHEMBL13634719 | 0.81 | HRH3 (0.39) | HRH3GPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |