Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 5/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634587 | 0.92 | GPR6 (0.36) | GPR6OPRK1KMT2ASCDIRAK4 | |
| SCHEMBL13634681 | 0.91 | HRH3 (0.38) | GPR6OPRK1KMT2ASCDIRAK4 | |
| SCHEMBL13638990 | 0.89 | MAP4K1 (0.38) | GPR6IRAK4 | |
| SCHEMBL13634800 | 0.87 | IRAK4 (0.46) | GPR6OPRK1KMT2AIRAK4 | |
| SCHEMBL13634885 | 0.86 | GLS (0.41) | GPR6GLSOPRK1KMT2ASCD | |
| SCHEMBL13634876 | 0.85 | GLS (0.41) | GPR6GLSOPRK1KMT2ASCD | |
| SCHEMBL13638779 | 0.85 | MAP4K1 (0.39) | GPR6FFAR1 | |
| SCHEMBL13638904 | 0.85 | MAP4K1 (0.39) | GPR6PIM2 | |
| SCHEMBL13634838 | 0.85 | SCD (0.41) | GPR6GLSOPRK1KMT2ASCD | |
| SCHEMBL13634642 | 0.84 | PARP1 (0.40) | GPR6GLSACKR3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |