Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 2/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 3/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638904 | 0.92 | MAP4K1 (0.39) | MAP4K1IDH1ADORA2AADORA1F10 | |
| SCHEMBL13638779 | 0.92 | MAP4K1 (0.39) | MAP4K1IDH1ADORA2AADORA1F10 | |
| SCHEMBL13634843 | 0.89 | GPR6 (0.38) | GPR6IRAK4 | |
| SCHEMBL13638885 | 0.86 | IRAK4 (0.47) | IRAK4 | |
| SCHEMBL13638937 | 0.86 | IRAK4 (0.38) | IDH1SYKIRAK4 | |
| SCHEMBL13634681 | 0.86 | HRH3 (0.38) | KDM4EHPGDGPR6IRAK4 | |
| SCHEMBL13634587 | 0.85 | GPR6 (0.36) | GPR6IRAK4 | |
| SCHEMBL13634599 | 0.85 | GPR6 (0.37) | GPR6 | |
| SCHEMBL13638914 | 0.84 | SCD (0.41) | GPR6IRAK4 | |
| SCHEMBL13638926 | 0.84 | GPR6 (0.37) | GPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |