Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | SCD | O00767 | 2/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13164107 | 0.93 | KDM4E (0.38) | ACKR3TBK1HRH3SCDSCD5 | |
| SCHEMBL13634575 | 0.93 | TBK1 (0.37) | ACKR3TBK1HRH3SCDSCD5 | |
| SCHEMBL13634913 | 0.93 | TBK1 (0.37) | ACKR3TBK1HRH3SCDSCD5 | |
| SCHEMBL13164106 | 0.93 | KDM4E (0.38) | ACKR3TBK1HRH3SCDSCD5 | |
| SCHEMBL13634659 | 0.89 | SCD (0.35) | HRH3SCDSCD5IRAK4CNR2 | |
| SCHEMBL13634897 | 0.89 | SCD (0.36) | HRH3SCDSCD5CNR2 | |
| SCHEMBL13634847 | 0.86 | IRAK4 (0.37) | SCDSCD5IRAK4 | |
| SCHEMBL13634846 | 0.86 | IRAK4 (0.37) | SCDSCD5IRAK4 | |
| SCHEMBL13634732 | 0.86 | CHEK1 (0.35) | SCDSCD5IRAK4 | |
| SCHEMBL13638833 | 0.85 | GRM2 (0.39) | ACKR3SCDSCD5PARP1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |