Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.33 |
| ▸ | SCD | O00767 | 2/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634575 | 1.00 | TBK1 (0.37) | TBK1ACKR3IRAK4HRH3GLS | |
| SCHEMBL13164106 | 0.95 | KDM4E (0.38) | TBK1ACKR3IRAK4HRH3USP30 | |
| SCHEMBL13164107 | 0.95 | KDM4E (0.38) | TBK1ACKR3IRAK4HRH3USP30 | |
| SCHEMBL13634691 | 0.93 | ACKR3 (0.38) | TBK1ACKR3IRAK4HRH3USP30 | |
| SCHEMBL13634669 | 0.89 | GLS (0.35) | IRAK4HRH3GLSSCDSCD5 | |
| SCHEMBL13634768 | 0.89 | GLS (0.35) | IRAK4HRH3GLSSCDSCD5 | |
| SCHEMBL13634906 | 0.87 | SCD (0.38) | HRH3GLSSCDSCD5PARP1 | |
| SCHEMBL13634933 | 0.86 | PDE4B (0.41) | ACKR3USP30TP53 | |
| SCHEMBL13634923 | 0.85 | CHEK1 (0.36) | IRAK4GLSSCDSCD5PARP1 | |
| SCHEMBL13634574 | 0.85 | CHEK1 (0.36) | IRAK4GLSSCDSCD5PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |