Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.36 |
| ▸ | NAPEPLD | Q6IQ20 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 4/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162061 | 0.86 | S1PR1 (0.35) | S1PR1NAPEPLDPIM1PIM3PIM2 | |
| SCHEMBL13634841 | 0.85 | S1PR1 (0.49) | S1PR1IRAK4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13634668 | 0.81 | F10 (0.37) | S1PR1F10IRAK4GAA | |
| SCHEMBL2770230 | 0.81 | S1PR1 (0.46) | S1PR1PIM1F10 | |
| SCHEMBL13638887 | 0.80 | S1PR1 (0.47) | S1PR1NAPEPLDIRAK4CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL2772517 | 0.79 | S1PR1 (0.47) | S1PR1F10 | |
| SCHEMBL2769811 | 0.79 | CHEK1 (0.41) | PIM1PIM3PIM2CNR2 | |
| SCHEMBL2771379 | 0.78 | TSHR (0.41) | S1PR1NAPEPLDIRAK4 | |
| SCHEMBL13634911 | 0.78 | KMT2A (0.45) | S1PR1NAPEPLDF10GAACYP1A2 | |
| SCHEMBL13634769 | 0.77 | HDAC3 (0.41) | PIM1F10IRAK4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |