Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 2/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | INSR | P06213 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638833 | 0.89 | GRM2 (0.39) | SCDSCD5PIM2PIM1PIM3 | |
| SCHEMBL13634588 | 0.89 | S1PR1 (0.41) | F10S1PR1SCDSCD5PIM2 | |
| SCHEMBL13634767 | 0.89 | SCD (0.37) | SCDSCD5PIM2PIM1PIM3 | |
| SCHEMBL13634897 | 0.88 | SCD (0.36) | S1PR1SCDSCD5MAPTPIM2 | |
| SCHEMBL13634927 | 0.87 | CNR2 (0.36) | SCDSCD5PIM2PIM1PIM3 | |
| SCHEMBL13634557 | 0.87 | S1PR1 (0.42) | S1PR1SCDSCD5CNR2 | |
| SCHEMBL13270650 | 0.86 | MAPT (0.39) | F10S1PR1SCDSCD5GAA | |
| SCHEMBL13634738 | 0.86 | GRM2 (0.35) | SCDSCD5GAAPIM2L3MBTL1 | |
| SCHEMBL13270715 | 0.85 | SCD (0.37) | SCDSCD5PIM2PIM1PIM3 | |
| SCHEMBL13270769 | 0.85 | ITK (0.36) | F10SCDSCD5MAPTPIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |