Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 2/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.33 |
| ▸ | PIM1 | P11309 | 3/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638833 | 0.96 | GRM2 (0.39) | GRM2PDCD1CD274SCDSCD5 | |
| SCHEMBL13634563 | 0.92 | PDCD1 (0.37) | GRM2PDCD1CD274SCDSCD5 | |
| SCHEMBL13270650 | 0.90 | MAPT (0.39) | SCDSCD5ALDH1A1LMNAKDM4E | |
| SCHEMBL13634767 | 0.90 | SCD (0.37) | SCDSCD5CNR2PIN1PIM1 | |
| SCHEMBL13634897 | 0.89 | SCD (0.36) | SCDSCD5MCHR1CNR2PIM1 | |
| SCHEMBL13634915 | 0.88 | LMNA (0.37) | PDCD1CD274SCDSCD5ALDH1A1 | |
| SCHEMBL13634927 | 0.88 | CNR2 (0.36) | SCDSCD5CNR2PIN1PIM1 | |
| SCHEMBL13638951 | 0.88 | PDCD1 (0.40) | GRM2PDCD1CD274SCDSCD5 | |
| SCHEMBL13634659 | 0.87 | SCD (0.35) | SCDSCD5CNR2PIN1PIM1 | |
| SCHEMBL13634641 | 0.87 | SCD (0.34) | GRM2SCDSCD5ALDH1A1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |