Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162967 | 0.95 | HDAC8 (0.50) | S1PR1HDAC8HDAC6HDAC1SIGMAR1 | |
| SCHEMBL13634595 | 0.88 | S1PR1 (0.49) | S1PR1HDAC8HDAC6HDAC1SIGMAR1 | |
| SCHEMBL13634686 | 0.87 | HDAC8 (0.47) | S1PR1HDAC8HDAC6HDAC1SIGMAR1 | |
| SCHEMBL13634729 | 0.87 | S1PR1 (0.45) | S1PR1HDAC8HDAC6HDAC1SIGMAR1 | |
| SCHEMBL13634841 | 0.84 | S1PR1 (0.49) | S1PR1HDAC8HDAC6HDAC1SIGMAR1 | |
| SCHEMBL13638884 | 0.83 | S1PR1 (0.47) | S1PR1HDAC8HDAC6HDAC1SIGMAR1 | |
| SCHEMBL13638916 | 0.82 | HDAC8 (0.43) | S1PR1HDAC8HDAC6HDAC1SIGMAR1 | |
| SCHEMBL13634557 | 0.80 | S1PR1 (0.42) | S1PR1HDAC8HDAC6HDAC1SIGMAR1 | |
| SCHEMBL13270465 | 0.80 | KMT2A (0.44) | — | |
| SCHEMBL13638887 | 0.79 | S1PR1 (0.47) | S1PR1HDAC8HDAC6HDAC1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |