Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 15/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634797 | 0.91 | IRAK4 (0.50) | IRAK4GPR55LMNAMAPTMEN1 | |
| SCHEMBL13270469 | 0.90 | IRAK4 (0.47) | IRAK4 | |
| SCHEMBL13634739 | 0.89 | IRAK4 (0.48) | IRAK4GPR55LMNAMAPTMEN1 | |
| SCHEMBL13634551 | 0.87 | IRAK4 (0.47) | IRAK4 | |
| SCHEMBL13634699 | 0.86 | IRAK4 (0.50) | IRAK4MAPT | |
| SCHEMBL13270468 | 0.83 | IRAK4 (0.46) | IRAK4LMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL13634900 | 0.80 | GRM2 (0.42) | IRAK4LMNAMAPTSMN1; SMN2 | |
| SCHEMBL13634721 | 0.80 | IRAK4 (0.49) | IRAK4MAPTALDH1A1 | |
| SCHEMBL13270595 | 0.78 | IRAK4 (0.44) | IRAK4 | |
| SCHEMBL13634720 | 0.78 | IRAK4 (0.47) | IRAK4MAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |