Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.41 |
| ▸ | DRD4 | P21917 | 11/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634943 | 0.94 | GRM2 (0.42) | GRM2IRAK4DRD4HRH3ACHE | |
| SCHEMBL13634742 | 0.91 | KMT2A (0.45) | GRM2IRAK4DRD4HRH3LMNA | |
| SCHEMBL13634629 | 0.91 | GRM2 (0.40) | GRM2IRAK4DRD4HRH3SMN1; SMN2 | |
| SCHEMBL13634784 | 0.80 | IRAK4 (0.51) | IRAK4LMNAMAPTSMN1; SMN2 | |
| SCHEMBL13634699 | 0.79 | IRAK4 (0.50) | GRM2IRAK4ACHEMAPT | |
| SCHEMBL13270469 | 0.77 | IRAK4 (0.47) | IRAK4ACHE | |
| SCHEMBL13634797 | 0.76 | IRAK4 (0.50) | IRAK4LMNAMAPTMAPK1 | |
| SCHEMBL13634781 | 0.75 | GPR6 (0.40) | IRAK4ACHE | |
| SCHEMBL13634721 | 0.74 | IRAK4 (0.49) | GRM2IRAK4MAPTMAPK1 | |
| SCHEMBL13162596 | 0.73 | DRD4 (0.50) | GRM2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |