Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638885 | 0.94 | IRAK4 (0.47) | IRAK4OPRK1KMT2AMAPK14IRAK1 | |
| SCHEMBL13634650 | 0.89 | IRAK4 (0.50) | IRAK4OPRK1KMT2AIRAK1 | |
| SCHEMBL13634783 | 0.89 | IRAK4 (0.48) | IRAK4OPRK1KMT2A | |
| SCHEMBL13634885 | 0.88 | GLS (0.41) | OPRK1KMT2AGPR6 | |
| SCHEMBL13634876 | 0.87 | GLS (0.41) | OPRK1KMT2AGPR6 | |
| SCHEMBL13634843 | 0.87 | GPR6 (0.38) | IRAK4OPRK1KMT2AGPR6 | |
| SCHEMBL13634838 | 0.86 | SCD (0.41) | IRAK4OPRK1KMT2AGPR6 | |
| SCHEMBL13634857 | 0.85 | GPR6 (0.39) | IRAK4OPRK1KMT2AMAPK14GPR6 | |
| SCHEMBL13634523 | 0.85 | IDH1 (0.38) | IRAK4OPRK1KMT2AMAPK14GPR6 | |
| SCHEMBL13634818 | 0.85 | MCHR1 (0.41) | GPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |