Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638910 | 0.94 | KMT2A (0.38) | GPR6IRAK4OPRK1KMT2APDE4B | |
| SCHEMBL13634753 | 0.90 | OPRK1 (0.39) | GPR6IRAK4OPRK1KMT2ASCD | |
| SCHEMBL13634800 | 0.85 | IRAK4 (0.46) | GPR6IRAK4OPRK1KMT2AMAPK14 | |
| SCHEMBL2772498 | 0.84 | PARP1 (0.43) | IRAK4OPRK1KMT2APDE4B | |
| SCHEMBL2770473 | 0.83 | KMT2A (0.44) | IRAK4OPRK1KMT2APDE4B | |
| SCHEMBL13634818 | 0.83 | MCHR1 (0.41) | GPR6SCD | |
| SCHEMBL13634642 | 0.82 | PARP1 (0.40) | GPR6 | |
| SCHEMBL13634617 | 0.82 | MCHR1 (0.39) | IRAK4OPRK1KMT2APDE4B | |
| SCHEMBL13634885 | 0.82 | GLS (0.41) | GPR6OPRK1KMT2ASCD | |
| SCHEMBL13634567 | 0.81 | MCHR1 (0.39) | IRAK4OPRK1KMT2APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |