Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162084 | 0.88 | ALDH1A1 (0.51) | ALDH1A1CHRNB4CHRNA3CYP1A2OPRM1 | |
| SCHEMBL21590257 | 0.81 | CHRNB4 (0.45) | CHRNB4CHRNA3CYP3A4OPRM1OPRD1 | |
| SCHEMBL13162085 | 0.80 | CHRNB4 (0.54) | ALDH1A1CHRNB4CHRNA3 | |
| SCHEMBL21590273 | 0.79 | KDM4E (0.46) | — | |
| SCHEMBL21590280 | 0.79 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL13162095 | 0.78 | CHRNB4 (0.62) | ALDH1A1CHRNB4CHRNA3 | |
| SCHEMBL12491226 | 0.77 | GRIN2D (0.43) | CYP3A4OPRM1OPRD1 | |
| SCHEMBL12090379 | 0.76 | CHRNB2 (0.62) | CHRNB4CHRNA3 | |
| SCHEMBL23036720 | 0.75 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL21491412 | 0.75 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |