Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL788804 | 0.89 | HSD11B1 (0.68) | HSD11B1 | |
| SCHEMBL793862 | 0.84 | HSD11B1 (0.67) | HSD11B1 | |
| SCHEMBL12640446 | 0.80 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL4384483 | 0.80 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL30674410 | 0.80 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL4378537 | 0.80 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL4377098 | 0.78 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL13635045 | 0.78 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL4392304 | 0.77 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL23815240 | 0.75 | HSD11B1 (0.83) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893609-B1 | N-(PYRIDIN-2-YL)-SULFONAMIDE DERIVATIVES | PFIZER (US) | 2009-11-18 | — | — | EP | disclosed |