SCHEMBL788804

SCHEMBL788804

N#Cc1ccc(-c2ccc(S(=O)(=O)Nc3cccc(C(=O)O)n3)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13634947 0.89 HSD11B1 (0.67) HSD11B1
SCHEMBL793862 0.87 HSD11B1 (0.67) HSD11B1
SCHEMBL4384483 0.81 HSD11B1 (1.00) HSD11B1
SCHEMBL30674410 0.81 HSD11B1 (1.00) HSD11B1
SCHEMBL12640446 0.81 HSD11B1 (1.00) HSD11B1
SCHEMBL4378537 0.81 HSD11B1 (1.00) HSD11B1
SCHEMBL13635045 0.79 HSD11B1 (1.00) HSD11B1
SCHEMBL4377098 0.79 HSD11B1 (1.00) HSD11B1
SCHEMBL4392304 0.78 HSD11B1 (1.00) HSD11B1
SCHEMBL23815240 0.76 HSD11B1 (0.83) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2616450-A2 SULFONAMIDE COMPOUNDS Kancera AB (SE) 2013-07-24 EP claimed
WO-2012035171-A2 NEW COMPOUNDS KANCERA AB (SE) 2012-03-22 WO claimed