Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13061912 | 0.94 | KDM4E (0.44) | CNR2P2RX4F10F2PRSS1 | |
| SCHEMBL13011699 | 0.90 | PLA2G2A (0.42) | CNR2P2RX4F10F2PRSS1 | |
| SCHEMBL13011675 | 0.88 | PLA2G2A (0.48) | CNR2F10F2PRSS1PLA2G2A | |
| SCHEMBL13062047 | 0.88 | P2RX4 (0.55) | CNR2P2RX4F10F2PRSS1 | |
| SCHEMBL13061918 | 0.83 | TP53 (0.47) | F10F2PRSS1ALDH1A1MAPT | |
| SCHEMBL3767125 | 0.82 | CYP19A1 (0.53) | CNR2P2RX4ALDH1A1MAPTKDM4E | |
| SCHEMBL13011683 | 0.80 | P2RX4 (0.52) | P2RX4ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL13011330 | 0.79 | ALDH1A1 (0.50) | P2RX4ALDH1A1MAPTKDM4EHCRTR1 | |
| SCHEMBL13011698 | 0.79 | HDAC6 (0.44) | P2RX4F10F2PRSS1KDM4E | |
| SCHEMBL13011656 | 0.78 | CNR2 (0.53) | CNR2MAPTHDAC3HDAC6HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119704-A1 | ACYLGUANIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-11-18 | — | — | EP | disclosed |