Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 4/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13011699 | 0.94 | PLA2G2A (0.42) | KDM4EHCRTR1ALDH1A1LMNAMAPT | |
| SCHEMBL13634968 | 0.94 | CNR2 (0.41) | KDM4EHCRTR1ALDH1A1LMNAMAPT | |
| SCHEMBL13011675 | 0.92 | PLA2G2A (0.48) | MAPTF10F2PRSS1PLA2G2A | |
| SCHEMBL13062047 | 0.92 | P2RX4 (0.55) | LMNAP2RX4F10F2PRSS1 | |
| SCHEMBL13061918 | 0.86 | TP53 (0.47) | ALDH1A1LMNAMAPTSMN1; SMN2F10 | |
| SCHEMBL3767125 | 0.85 | CYP19A1 (0.53) | KDM4EALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL13011330 | 0.84 | ALDH1A1 (0.50) | KDM4EHCRTR1ALDH1A1LMNAMAPT | |
| SCHEMBL13011683 | 0.84 | P2RX4 (0.52) | KDM4EALDH1A1LMNAMAPTP2RX4 | |
| SCHEMBL13011336 | 0.83 | MAPT (0.51) | KDM4EHCRTR1ALDH1A1LMNAMAPT | |
| SCHEMBL13011698 | 0.82 | HDAC6 (0.44) | KDM4ELMNAP2RX4F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324017-A1 | ACYLGUANIDINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324017-A1 | ACYLGUANIDINE DERIVATIVE | HTR5A, GRM5, HTR1E | KDM4E 731/4885HCRTR1 840/4885ALDH1A1 2104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.