Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 3/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14640138 | 0.85 | ALDH1A1 (0.33) | — | |
| SCHEMBL14640151 | 0.85 | ALDH1A1 (0.33) | — | |
| SCHEMBL1677572 | 0.80 | BCHE (0.41) | BDKRB2EPHX1MAPT | |
| SCHEMBL1677604 | 0.79 | P2RX7 (0.42) | MAPT | |
| SCHEMBL1678007 | 0.75 | LMNA (0.42) | MAPT | |
| SCHEMBL1678957 | 0.73 | P2RX7 (0.43) | MAPT | |
| SCHEMBL14419716 | 0.71 | ALDH1A1 (0.35) | EPHX1 | |
| SCHEMBL1678024 | 0.71 | MEN1 (0.44) | — | |
| SCHEMBL1678250 | 0.71 | P2RX7 (0.43) | MAPT | |
| SCHEMBL14640129 | 0.70 | CYP17A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1743885-B1 | 1-[(adamantyl)alkyl]-3-[(pyridinyl)alkyl]urea compounds as TNF-.alpha inhibitors useful for autoimmune diseases | SANTEN PHARMACEUTICAL CO LTD (JP) | 2009-11-11 | — | — | EP | disclosed |