Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13635119 | 0.84 | PTGER4 (0.73) | PTGER4MEN1KMT2AAPPMAPT | |
| SCHEMBL13011247 | 0.80 | KDM4E (0.57) | PTGER4MEN1KMT2APSEN1PSEN2 | |
| SCHEMBL13634962 | 0.79 | PTGER4 (0.61) | PTGER4MEN1KMT2APOLBMAPT | |
| SCHEMBL13635107 | 0.78 | MEN1 (0.47) | PTGER4MEN1KMT2APTGS2POLB | |
| SCHEMBL13011160 | 0.78 | SCARB1 (0.50) | PTGER4MEN1KMT2APTGS2PSEN1 | |
| SCHEMBL28899271 | 0.77 | PTGER4 (0.58) | PTGER4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL13387565 | 0.77 | PTGER4 (0.85) | PTGER4MEN1KMT2AAPPPOLB | |
| SCHEMBL30295042 | 0.77 | PTGER4 (0.85) | PTGER4MEN1KMT2AAPPPOLB | |
| SCHEMBL12479908 | 0.77 | PTGER4 (0.85) | PTGER4MEN1KMT2AAPPPOLB | |
| SCHEMBL7172636 | 0.76 | PTGER4 (0.61) | PTGER4MEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119704-A1 | ACYLGUANIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-11-18 | — | — | EP | disclosed |