SCHEMBL1363588

SCHEMBL1363588

NNC(=O)c1cccc(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 1.00
KDM4E B2RXH2 5/20 1.00
EGLN2 Q96KS0 1/20 0.68
PARP1 P09874 1/20 0.61
GFER P55789 3/20 0.57
BLM P54132 2/20 0.57
CA12 O43570 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA6 P23280 1/20 0.57
CA9 Q16790 1/20 0.57
MPO P05164 1/20 0.57
CYP3A4 P08684 1/20 0.57
KDM5A P29375 1/20 0.57
PMP22 Q01453 1/20 0.57
HIF1A Q16665 1/20 0.57
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
AOC2 O75106 1/20 0.56
NPC1 O15118 5/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3973558 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EEGLN2PARP1GFER
SCHEMBL77384 0.87 ALDH1A1 (0.76) ALDH1A1KDM4EGFERBLMMPO
Water SCHEMBL8856509 0.85 ALDH1A1 (0.73) ALDH1A1KDM4EEGLN2PARP1GFER
SCHEMBL11327878 0.85 KDM4E (0.76) ALDH1A1KDM4EEGLN2PARP1GFER
SCHEMBL1904111 0.83 ALDH1A1 (0.70) ALDH1A1KDM4EGFERBLMCA1
SCHEMBL23484191 0.82 KDM4E (0.69) ALDH1A1KDM4EEGLN2PARP1CA12
Benzoic Acid Hydrazide SCHEMBL28939025 0.81 MPO (0.72) ALDH1A1KDM4EGFERBLMCA12
SCHEMBL25700071 0.81 ALDH1A1 (0.68) ALDH1A1KDM4EGFERBLMMPO
SCHEMBL28254875 0.81 ALDH1A1 (0.68) ALDH1A1KDM4EGFERBLMMPO
SCHEMBL2872684 0.81 KDM4E (1.00) ALDH1A1KDM4EEGLN2PARP1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3494396-B1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF PIERCE BIOTECHNOLOGY INC (US) 2025-06-11 EP claimed
CN-118637938-B Preparation method of carbon/carbon composite material 湖州幄肯中欣新能源科技有限公司 2024-10-29 CN claimed
CN-118637938-A Preparation method of carbon/carbon composite material 湖州幄肯中欣新能源科技有限公司 2024-09-13 CN claimed
WO-2022268087-A1 HIGH-TEMPERATURE-RESISTANT SILICON DIOXIDE GRAFTED TERTIARY AMINE NANOPARTICLE PLUGGING AGENT AND WATER-BASED DRILLING FLUID 西南石油大学 2022-12-29 WO claimed
CN-113416315-B Hyperbranched poly-tertiary amine shale inhibitor 西南石油大学 2022-09-30 CN claimed
US-11398630-B2 Method of generating energy from a hydrazide containing anode fuel, and fuel cell IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2022-07-26 US claimed
CN-113292973-B High-temperature-resistant silica-grafted tertiary amine nano plugging agent and water-based drilling fluid 西南石油大学 2022-04-01 CN claimed
CN-113416524-A High-temperature-resistant hyperbranched poly-tertiary amine as shale inhibitor 西南石油大学 2021-09-21 CN claimed
CN-113416315-A Hyperbranched poly-tertiary amine shale inhibitor 西南石油大学 2021-09-21 CN claimed
CN-113292973-A High-temperature-resistant silica-grafted tertiary amine nano plugging agent and water-based drilling fluid 西南石油大学 2021-08-24 CN claimed
US-20160297732-A1 METHOD FOR MANUFACTURING HIGH PURITY GLYCOL BASED COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-13 US claimed
WO-2006076034-A2 STABILIZED TWO COMPONENT SYSTEM FOR CHEMILUMIESCENT ASSAY IN IMMUNODIAGNOSTICS BHANU, KALRA (US) 2006-07-20 WO claimed
EP-1254252-A4 NOVEL STABILIZED FORMULATIONS FOR CHEMILUMINESCENT ASSAYS GIRI BRIJ P (US) 2006-06-07 EP claimed
US-20050272108-A1 Stabilized two component system for chemiluminescent assay in immunodiagnostics KALRA BHANU 2005-12-08 US claimed
US-20030105140-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. 2003-06-05 US claimed
WO-2002102301-A2 SUBSTITUTED INDOLE-2-CARBOXYLIC ACID BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF CYTOVIA, INC. (US) 2002-12-27 WO claimed
US-20020128292-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. 2002-09-12 US claimed
US-6337368-B1 WATER INSOLUBLE CARRIERS WITH P-NITROBENZOIC ACID, AROMATIC AMINES, AMIDES, SULFONAMIDES AND HYDRAZIDES KANEKA CORPORATION (JP) 2002-01-08 US claimed
US-20010046688-A1 Novel stabilized formulations for chemiluminescent assays GIRI BRIJ PAL (US) 2001-11-29 US claimed
WO-2001055446-A1 NOVEL STABILIZED FORMULATIONS FOR CHEMILUMINESCENT ASSAYS GIRI BRIJ PAL (US) 2001-08-02 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020128292-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof BAD, API5, CASP2 ALDH1A1 144/4885KDM4E 2887/4885EGLN2 194/4885
US-20030105140-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof BAD, API5, CASP2 ALDH1A1 144/4885KDM4E 2887/4885EGLN2 194/4885
US-20160297732-A1 METHOD FOR MANUFACTURING HIGH PURITY GLYCOL BASED COMPOUND GK, GMDS, UGCG ALDH1A1 87/4885KDM4E 2823/4885EGLN2 869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.