Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761123 | 0.75 | IDO1 (0.47) | FFAR1PPARGPPARA | |
| SCHEMBL5758636 | 0.74 | TRPA1 (0.47) | PPARGPPARA | |
| SCHEMBL12820168 | 0.72 | CNR1 (0.44) | — | |
| SCHEMBL18747194 | 0.68 | HTR2A (0.48) | PPARA | |
| SCHEMBL19546875 | 0.67 | LOXL2 (0.46) | — | |
| SCHEMBL10187262 | 0.67 | NQO1 (0.50) | FFAR1 | |
| SCHEMBL5710979 | 0.66 | TAAR1 (0.52) | PPARA | |
| SCHEMBL13516238 | 0.66 | PPARA (0.42) | PPARGPPARA | |
| SCHEMBL24036410 | 0.66 | PPARD (0.32) | FFAR1PPARA | |
| SCHEMBL12655428 | 0.66 | HRH4 (0.32) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143211-A2 | SALTS OF 2-FLUORO-N-METHYL-4-[7-(QUINOLIN-6-YL-METHYL)- IMIDAZO[1,2-B][1,2,4]TRIAZIN-2-YL]BENZAMIDE AND PROCESSES RELATED TO PREPARING THE SAME | INCYTE CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |