Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.44 |
| ▸ | KCND2 | Q9NZV8 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4384250 | 0.88 | KMT2A (0.64) | KMT2AALDH1A1TSHRMEN1SHMT2 | |
| SCHEMBL4375522 | 0.87 | KMT2A (0.62) | KMT2AALDH1A1TSHRMEN1SHMT2 | |
| Hydrochloric Acid SCHEMBL4378950 | 0.86 | KMT2A (0.61) | KMT2AALDH1A1TSHRMEN1SHMT2 | |
| SCHEMBL4375187 | 0.83 | KMT2A (0.73) | KMT2AALDH1A1TSHRMEN1SHMT2 | |
| SCHEMBL4377238 | 0.82 | KMT2A (0.71) | KMT2AALDH1A1TSHRMEN1SHMT2 | |
| SCHEMBL4384401 | 0.78 | ALDH1A1 (0.51) | KMT2AALDH1A1TSHRMEN1SHMT2 | |
| SCHEMBL2832797 | 0.78 | KMT2A (0.52) | KMT2AALDH1A1TSHRMEN1 | |
| Hydrochloric Acid SCHEMBL4384398 | 0.77 | KCNA5 (0.50) | KMT2AALDH1A1TSHRMEN1SHMT2 | |
| SCHEMBL4379159 | 0.73 | ALDH1A1 (0.87) | KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL2833221 | 0.73 | L3MBTL3 (0.59) | KMT2AALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421071-B1 | SUBSTITUTED PIPERAZINE AND DIAZEPANE DERIVAIVES AS HISTAMINE H3 RECEPTOR MODULATORS | HIGH POINT PHARMACEUTICALS LLC (US) | 2009-11-18 | — | — | EP | disclosed |