Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | C3AR1 | Q16581 | 5/20 | 0.47 |
| ▸ | TRPV6 | Q9H1D0 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4384086 | 0.87 | C3AR1 (0.62) | C3AR1KMT2AALDH1A1KDM4ETSHR | |
| SCHEMBL4382207 | 0.85 | C3AR1 (0.61) | C3AR1KMT2AALDH1A1KDM4ETSHR | |
| SCHEMBL2831484 | 0.76 | C3AR1 (0.61) | C3AR1 | |
| SCHEMBL4377443 | 0.71 | TRPV6 (0.52) | POLBTRPV6KMT2AALDH1A1KDM4E | |
| SCHEMBL31329931 | 0.69 | TRPV6 (0.80) | TRPV6ALDH1A1KDM4E | |
| SCHEMBL31329872 | 0.69 | TRPV6 (0.62) | TRPV6 | |
| SCHEMBL10305181 | 0.68 | NPC1 (0.67) | C3AR1 | |
| SCHEMBL28283653 | 0.67 | CHRNB2 (0.71) | TRPV6ALDH1A1KDM4E | |
| SCHEMBL29615692 | 0.67 | TRPV6 (0.62) | POLBTRPV6KMT2AALDH1A1KDM4E | |
| SCHEMBL29615698 | 0.67 | TRPV6 (0.62) | POLBTRPV6KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421071-B1 | SUBSTITUTED PIPERAZINE AND DIAZEPANE DERIVAIVES AS HISTAMINE H3 RECEPTOR MODULATORS | HIGH POINT PHARMACEUTICALS LLC (US) | 2009-11-18 | — | — | EP | disclosed |