Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 3/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13163967 | 0.91 | CASP3 (0.57) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL2313063 | 0.91 | CASP3 (0.57) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL29361981 | 0.91 | CASP3 (0.57) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL7423417 | 0.91 | CASP3 (0.57) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL29386346 | 0.91 | CASP3 (0.57) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL29423514 | 0.91 | CASP3 (0.57) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL29008318 | 0.90 | MDM4 (0.50) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL8303670 | 0.90 | MDM4 (0.50) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL30384784 | 0.90 | MDM4 (0.50) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL2439000 | 0.90 | MDM4 (0.50) | MDM4TP53CASP3MDM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8303956-B2 | Glycosylated specificity exchangers | CHRONTECH PHARMA AB (SE) | 2012-11-06 | — | — | US | disclosed |