SCHEMBL29361981

SCHEMBL29361981

CC(C)(C)OC(=O)[C@@H](CC(=O)O)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CASP3 P42574 4/20 0.57
▸ MDM4 O15151 2/20 0.53
▸ TP53 P04637 2/20 0.53
▸ MDM2 Q00987 1/20 0.51
▸ KMT2A Q03164 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29423514 1.00 CASP3 (0.57) CASP3MDM4TP53MDM2KMT2A
SCHEMBL29386346 1.00 CASP3 (0.57) CASP3MDM4TP53MDM2KMT2A
SCHEMBL7423417 1.00 CASP3 (0.57) CASP3MDM4TP53MDM2KMT2A
SCHEMBL2313063 1.00 CASP3 (0.57) CASP3MDM4TP53MDM2KMT2A
SCHEMBL13163967 1.00 CASP3 (0.57) CASP3MDM4TP53MDM2KMT2A
SCHEMBL29511158 0.91 CASP3 (0.52) CASP3MDM4TP53MDM2KMT2A
SCHEMBL8350965 0.91 CASP3 (0.52) CASP3MDM4TP53MDM2KMT2A
SCHEMBL13636676 0.91 MDM4 (0.51) CASP3MDM4TP53MDM2KMT2A
SCHEMBL18358965 0.91 CASP3 (0.55) CASP3MDM4TP53MDM2KMT2A
SCHEMBL29477062 0.90 MDM4 (0.55) CASP3MDM4TP53MDM2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12576169-B2 Silicon-fluoride acceptor substituted radiopharmaceuticals and precursors thereof Technische Universität München (DE) 2026-03-17 — — US disclosed
EP-4704874-A2 MOLECULES AND METHODS OF USE THEREOF Woolwich Sciences LLC (US) 2026-03-11 — — EP disclosed
EP-4508235-A2 PAPB AS A BIMOIETY-DEPENDENT THIOETHER INSTALLATION TOOL University of Utah Research Foundation (US) 2025-02-19 — — EP disclosed
WO-2025013923-A1 METHOD FOR LABELING ISOASPARTIC ACID (Lβ-ASPARTIC ACID) RESIDUE 国立研究開発法人 産業技術総合研究所 2025-01-16 — — WO disclosed
WO-2024226545-A2 MOLECULES AND METHODS OF USE THEREOF WOOLWICH SCIENCES LLC (US) 2024-10-31 — — WO disclosed
US-20240317780-A1 RADIOPHARMACEUTICAL SOMATOSTATIN RECEPTOR LIGANDS AND PRECURSORS THEREOF Technische Universität München (DE) 2024-09-26 — — US disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
EP-4337270-A1 RADIOPHARMACEUTICAL SOMATOSTATIN RECEPTOR LIGANDS AND PRECURSORS THEREOF Technische Universität München (DE) 2024-03-20 — — EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
CN-117320759-A Radiopharmaceutical somatostatin receptor ligands and precursors thereof 慕尼黑工业大学 2023-12-29 — — CN disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 — — CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
US-11629201-B2 PSMA-binding agents and uses thereof ITM Isotope Technologies Munich SE (DE) 2023-04-18 — — US disclosed
CN-110740757-B Novel PSMA-binding agents and uses thereof 同位素技术慕尼黑公司 2023-04-04 — — CN disclosed
WO-2022238553-A1 RADIOPHARMACEUTICAL SOMATOSTATIN RECEPTOR LIGANDS AND PRECURSORS THEREOF Technische Universität München (DE) 2022-11-17 — — WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
US-11299480-B2 2-arylsulfonamido-N-arylacetamide derivatized STAT3 inhibitors UNIVERSITY OF HAWAII (US) 2022-04-12 — — US disclosed
US-20220096669-A1 SILICON-FLUORIDE ACCEPTOR SUBSTITUTED RADIOPHARMACEUTICALS AND PRECURSORS THEREOF Technische Universität München (DE) 2022-03-31 — — US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed
US-20220024882-A1 NOVEL TUMOR ANTIGEN BINDING AGENTS AND USES THEREOF LSI FINANCING LLC, AS ADMINISTRATIVE AGENT 2022-01-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11299480-B2 2-arylsulfonamido-N-arylacetamide derivatized STAT3 inhibitors STAT3, JAK2, STAT5A CASP3 1275/4885MDM4 3843/4885TP53 33/4885
US-20220096669-A1 SILICON-FLUORIDE ACCEPTOR SUBSTITUTED RADIOPHARMACEUTICALS AND PRECURSORS THEREOF FOLH1, KLK3, FRS2 CASP3 4055/4885MDM4 3612/4885TP53 458/4885
US-11629201-B2 PSMA-binding agents and uses thereof FOLH1, PSMA3, PSMA2 CASP3 3020/4885MDM4 513/4885TP53 205/4885
US-20220024882-A1 NOVEL TUMOR ANTIGEN BINDING AGENTS AND USES THEREOF CD74, MICA, CD2BP2 CASP3 4252/4885MDM4 1065/4885TP53 4/4885
US-20240317780-A1 RADIOPHARMACEUTICAL SOMATOSTATIN RECEPTOR LIGANDS AND PRECURSORS THEREOF SSTR1, SSTR3, SSTR4 CASP3 4196/4885MDM4 1685/4885TP53 455/4885
US-12576169-B2 Silicon-fluoride acceptor substituted radiopharmaceuticals and precursors thereof KLK3, FOLH1, SLC7A1 CASP3 3478/4885MDM4 4308/4885TP53 493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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