SCHEMBL29386346

SCHEMBL29386346

CC(C)(C)OC(=O)[C@H](CC(=O)O)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CASP3 P42574 4/20 0.57
▸ MDM4 O15151 2/20 0.53
▸ TP53 P04637 2/20 0.53
▸ MDM2 Q00987 1/20 0.51
▸ KMT2A Q03164 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29423514 1.00 CASP3 (0.57) CASP3MDM4TP53MDM2KMT2A
SCHEMBL7423417 1.00 CASP3 (0.57) CASP3MDM4TP53MDM2KMT2A
SCHEMBL2313063 1.00 CASP3 (0.57) CASP3MDM4TP53MDM2KMT2A
SCHEMBL13163967 1.00 CASP3 (0.57) CASP3MDM4TP53MDM2KMT2A
SCHEMBL29361981 1.00 CASP3 (0.57) CASP3MDM4TP53MDM2KMT2A
SCHEMBL29511158 0.91 CASP3 (0.52) CASP3MDM4TP53MDM2KMT2A
SCHEMBL8350965 0.91 CASP3 (0.52) CASP3MDM4TP53MDM2KMT2A
SCHEMBL13636676 0.91 MDM4 (0.51) CASP3MDM4TP53MDM2KMT2A
SCHEMBL18358965 0.91 CASP3 (0.55) CASP3MDM4TP53MDM2KMT2A
SCHEMBL29477062 0.90 MDM4 (0.55) CASP3MDM4TP53MDM2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120137003-A Method for chemically synthesizing glycosylated insulin 中国医学科学院药物研究所 2025-06-13 — — CN claimed
CN-120118155-A PD-L1 targeted polypeptide positron probe and preparation method and application thereof 南方医科大学南方医院 2025-06-10 — — CN claimed
CN-118994308-A Industrial preparation method of small peptide for promoting wound healing 广州优然生物科技有限公司 2024-11-22 — — CN claimed
CN-112638934-B Solution phase Path for WNT hexapeptide 温特研究公司 2024-06-11 — — CN claimed
US-11970551-B2 Solution phase routes for WNT hexapeptides WNTRESEARCH AB (SE) 2024-04-30 — — US claimed
CN-117865829-A Preparation method of N- (9-fluorenylmethoxycarbonyl) -aspartic acid-1-tert-butyl ester 吉尔生化(上海)有限公司 2024-04-12 — — CN claimed
CN-117683114-A Preparation method of thymalfasin 江苏诺泰澳赛诺生物制药股份有限公司 2024-03-12 — — CN claimed
US-20240067694-A1 SYNTHESIS OF TEDUGLUTIDE BIOCON LIMITED (IN) 2024-02-29 — — US claimed
US-20230295232-A1 SOLUTION PHASE ROUTES FOR WNT HEXAPEPTIDES WNTRESEARCH AB (SE) 2023-09-21 — — US claimed
EP-3841107-B1 SOLUTION PHASE ROUTES FOR WNT HEXAPEPTIDES WNTRESEARCH AB (SE) 2023-06-28 — — EP claimed
EP-4722229-A1 ADAPTOR MOLECULES FOR TARGETED CELL IMMUNOTHERAPIES Universität Zürich (CH) 2026-04-08 — — EP disclosed
EP-4720072-A2 RAS INHIBITORS Revolution Medicines, Inc. (US) 2026-04-08 — — EP disclosed
US-20260042795-A1 DIPROPYLAMINE AS BASE FOR THE USE IN FMOC DEPROTECTION IN SOLID-PHASE PEPTIDE SYNTHESIS Universität Bern (CH) 2026-02-12 — — US disclosed
CN-120757472-A Method suitable for industrial production of aspartic acid derivative 成都市科隆化学品有限公司 2025-10-10 — — CN disclosed
EP-4611793-A1 INSULIN DERIVATIVES Ustav organicke chemie a biochemie Akademie ved CR, v.v.i. (CZ) 2025-09-10 — — EP disclosed
EP-3972694-A1 IMMUNOMODULATORS Bristol-Myers Squibb Company (US) 2022-03-30 — — EP disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed
WO-2022047517-A1 DERIVATISATION OF PEPTIDES AND PROTEINS FLOREY INSTITUTE FOR NEUROSCIENCE AND MENTAL HEALTH (AU) 2022-03-10 — — WO disclosed
CN-114075274-A Somarunotide analog and preparation method and application thereof 浙江湃肽生物有限公司深圳分公司 2022-02-22 — — CN disclosed
CN-114014843-A PSMA (patterned beam-selective membrane antigen) targeted nuclide/fluorescent bimodal ligand, molecular probe and application 北京大学第一医院 2022-02-08 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042795-A1 DIPROPYLAMINE AS BASE FOR THE USE IN FMOC DEPROTECTION IN SOLID-PHASE PEPTIDE SYNTHESIS PTMS, PEPD, ASNS CASP3 4268/4885MDM4 538/4885TP53 2254/4885
US-20240067694-A1 SYNTHESIS OF TEDUGLUTIDE DNPEP, GCLC, PTMS CASP3 446/4885MDM4 2266/4885TP53 1584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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