Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3490918 | 0.84 | ALDH1A1 (0.59) | RAB9ASMN1; SMN2TSHRMAPTPOLB | |
| SCHEMBL8042616 | 0.82 | ALDH1A1 (0.59) | RAB9ASMN1; SMN2TSHRMAPTPOLB | |
| SCHEMBL8058314 | 0.81 | ALDH1A1 (0.55) | RAB9ASMN1; SMN2TSHRMAPTPOLB | |
| SCHEMBL8055690 | 0.81 | TRPM8 (0.51) | RAB9ASMN1; SMN2TSHRMAPTPOLB | |
| SCHEMBL6030751 | 0.79 | ALDH1A1 (0.57) | RAB9ASMN1; SMN2TSHRMAPTPOLB | |
| SCHEMBL3494674 | 0.78 | MAPT (0.47) | RAB9ASMN1; SMN2TSHRMAPTPOLB | |
| SCHEMBL20154271 | 0.77 | RAB9A (0.59) | RAB9ASMN1; SMN2TSHRMAPTPOLB | |
| SCHEMBL6030484 | 0.76 | MAPT (0.48) | RAB9ASMN1; SMN2TSHRMAPTPOLB | |
| SCHEMBL25106703 | 0.76 | RAB9A (0.50) | RAB9ASMN1; SMN2TSHRMAPTPOLB | |
| SCHEMBL6029258 | 0.75 | MAPT (0.47) | RAB9ASMN1; SMN2TSHRMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123652-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-11-25 | — | — | EP | disclosed |