SCHEMBL29606754

SCHEMBL29606754

c1ccc(NCc2ccc3ccccc3c2)cc1

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.67
INSR P06213 1/20 0.60
IGF1R P08069 1/20 0.60
MAOB P27338 1/20 0.57
MRGPRX4 Q96LA9 1/20 0.54
MC4R P32245 2/20 0.53
MC5R P33032 2/20 0.53
HDAC1 Q13547 2/20 0.50
CYP1A2 P05177 2/20 0.50
MAPT P10636 1/20 0.50
MC3R P41968 1/20 0.50
MEN1 O00255 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
KMT2A Q03164 1/20 0.50
CYP2A6 P11509 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9093298 1.00 FFAR1 (0.67) FFAR1INSRIGF1RMAOBMRGPRX4
SCHEMBL20036943 0.88 INSR (0.75) FFAR1INSRIGF1RMRGPRX4MC4R
SCHEMBL27527525 0.85 FFAR1 (0.60) FFAR1INSRIGF1RMRGPRX4MC4R
SCHEMBL9702743 0.85 INSR (0.67) FFAR1INSRIGF1RMRGPRX4MC4R
SCHEMBL28392967 0.85 HTT (0.62) FFAR1INSRIGF1RMRGPRX4MC4R
Hydrochloric Acid SCHEMBL6419281 0.84 FFAR1 (0.58) FFAR1INSRIGF1RMRGPRX4MC4R
SCHEMBL13636688 0.83 MAPT (0.65) FFAR1INSRIGF1RCYP1A2MAPT
SCHEMBL20997736 0.83 INSR (0.55) FFAR1INSRIGF1RMRGPRX4MC4R
SCHEMBL30301284 0.81 FFAR1 (0.56) FFAR1INSRIGF1RMAOBMRGPRX4
SCHEMBL6542369 0.81 L3MBTL1 (0.60) FFAR1MAOBMC4RMC5RCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114409493-B Method for synthesizing 9-aryl fluorene compound 浙江工业大学 2024-02-23 CN disclosed
CN-114409493-A Method for synthesizing 9-aryl fluorene compound 浙江工业大学 2022-04-29 CN disclosed