SCHEMBL13636756

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13636778	0.86	NFE2L2 (0.49)	NFE2L2PTGS1CYP1A1CYP1B1APP
	SCHEMBL12887521	0.80	CYP1A2 (0.52)	CYP1A2APPRELANR1H2NR1H3
	SCHEMBL13636758	0.80	CYP1A2 (0.52)	CYP1A2APPRELANR1H2NR1H3
	SCHEMBL15681222	0.80	CYP1A2 (0.52)	CYP1A2APPRELANR1H2NR1H3
	SCHEMBL13636751	0.79	NFE2L2 (0.76)	NFE2L2PTGS1PTGS2APPKCNH2
	SCHEMBL10299915	0.79	CYP1A2 (0.47)	PTGS1PTGS2CYP1A2APPRELA
	SCHEMBL14526427	0.78	NFE2L2 (0.66)	NFE2L2PTGS1PTGS2CYP1A2CYP1A1
	SCHEMBL13636785	0.76	NFE2L2 (0.47)	NFE2L2PTGS1PTGS2CYP1A2CYP1A1
	SCHEMBL13636795	0.76	AHR (0.47)	NFE2L2PTGS1CYP1A2CYP1A1CYP1B1
	SCHEMBL13636748	0.75	PTGS1 (0.42)	NFE2L2PTGS1PTGS2CYP1A2APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.