Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13615208 | 0.90 | ALOX5AP (0.38) | APPALOX5APFEN1ALDH1A1CYP3A4 | |
| SCHEMBL19844726 | 0.90 | FASN (0.36) | APPALOX5APFEN1ALDH1A1CYP3A4 | |
| SCHEMBL13636638 | 0.88 | ALDH1A1 (0.33) | ALDH1A1TLR9TLR8TLR7 | |
| SCHEMBL13615184 | 0.87 | CYP2C9 (0.39) | APPALOX5APFEN1ALDH1A1CYP3A4 | |
| SCHEMBL13002302 | 0.87 | FASN (0.35) | APPALOX5APFEN1ALDH1A1CYP3A4 | |
| SCHEMBL19844731 | 0.86 | FASN (0.35) | APPALOX5APFEN1ALDH1A1CYP3A4 | |
| SCHEMBL8101981 | 0.84 | ALDH1A1 (0.37) | ALDH1A1TLR9TLR8TLR7 | |
| SCHEMBL8101984 | 0.84 | ALDH1A1 (0.37) | ALDH1A1TLR9TLR8TLR7 | |
| SCHEMBL20111107 | 0.82 | OPRM1 (0.33) | ALDH1A1CYP3A4CYP2C9TLR9TLR8 | |
| SCHEMBL16574959 | 0.81 | ALDH1A1 (0.35) | ALDH1A1TLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123623-A1 | LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2009-11-25 | — | — | EP | disclosed |