SCHEMBL13636638

SCHEMBL13636638

CCC1CCC(c2cc(F)c(-c3cc(F)c(C)c(F)c3)c(F)c2)CC1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
OPRM1 P35372 1/20 0.32
OPRK1 P41145 1/20 0.32
TLR9 Q9NR96 1/20 0.32
TLR8 Q9NR97 1/20 0.32
TLR7 Q9NYK1 1/20 0.32
TRPV3 Q8NET8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20111107 0.91 OPRM1 (0.33) ALDH1A1OPRM1OPRK1TLR9TLR8
SCHEMBL15965525 0.89 ALDH1A1 (0.33) ALDH1A1TLR9TLR8TLR7TRPV3
SCHEMBL18083580 0.89 ALDH1A1 (0.33) ALDH1A1TLR9TLR8TLR7TRPV3
SCHEMBL16841962 0.88 CYP2C9 (0.40) ALDH1A1OPRM1OPRK1TLR9TLR8
SCHEMBL13636825 0.88 APP (0.35) ALDH1A1TLR9TLR8TLR7
SCHEMBL16574959 0.87 ALDH1A1 (0.35) ALDH1A1TLR9TLR8TLR7TRPV3
SCHEMBL19844712 0.86 OPRM1 (0.34) OPRM1OPRK1TRPV3
SCHEMBL19844739 0.86 CYP2C9 (0.35) ALDH1A1OPRM1OPRK1TRPV3
SCHEMBL16488482 0.85 ALDH1A1 (0.32) ALDH1A1
SCHEMBL13002695 0.84 PDE2A (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2123623-A1 LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT Chisso Corporation (JP) 2009-11-25 EP disclosed