Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12230850 | 0.84 | NFE2L2 (0.46) | PTGS2PTGS1PDE3BPDE3ARPS6KA3 | |
| SCHEMBL20888423 | 0.84 | NFE2L2 (0.46) | PTGS2PTGS1PDE3BPDE3ARPS6KA3 | |
| SCHEMBL11957388 | 0.84 | NFE2L2 (0.46) | PTGS2PTGS1PDE3BPDE3ARPS6KA3 | |
| SCHEMBL4434166 | 0.84 | NFE2L2 (0.46) | PTGS2PTGS1PDE3BPDE3ARPS6KA3 | |
| SCHEMBL12976627 | 0.83 | PDK2 (0.37) | PTGS2PTGS1PDE3BPDE3ARPS6KA3 | |
| SCHEMBL13636716 | 0.83 | NFE2L2 (0.44) | PTGS2PTGS1PDE3BPDE3ARPS6KA3 | |
| SCHEMBL13636584 | 0.82 | RARB (0.40) | — | |
| SCHEMBL170435 | 0.80 | PDE3B (0.49) | PTGS2PTGS1PDE3BPDE3ARPS6KA3 | |
| SCHEMBL10024800 | 0.79 | PDE3B (0.42) | PTGS2PTGS1PDE3BPDE3ARPS6KA3 | |
| SCHEMBL2741547 | 0.79 | PDE3B (0.42) | PTGS2PTGS1PDE3BPDE3ARPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123623-A1 | LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2009-11-25 | — | — | EP | disclosed |