Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13636575 | 0.92 | NFE2L2 (0.50) | NFE2L2PTGS2RPS6KA3PTGS1AR | |
| SCHEMBL12976582 | 0.84 | NFE2L2 (0.41) | NFE2L2PDE3BPDE3AAKR1C3AKR1C2 | |
| SCHEMBL12230850 | 0.83 | NFE2L2 (0.46) | NFE2L2PDE3BPDE3APTGS2RPS6KA3 | |
| SCHEMBL15172775 | 0.83 | PDE3B (0.40) | NFE2L2PDE3BPDE3AAKR1C3AKR1C2 | |
| SCHEMBL4434166 | 0.83 | NFE2L2 (0.46) | NFE2L2PDE3BPDE3APTGS2RPS6KA3 | |
| SCHEMBL13636826 | 0.83 | PTGS2 (0.41) | NFE2L2PDE3BPDE3AESR1ESR2 | |
| SCHEMBL13636578 | 0.83 | NFE2L2 (0.45) | NFE2L2PTGS2RPS6KA3PTGS1AR | |
| SCHEMBL11957388 | 0.83 | NFE2L2 (0.46) | NFE2L2PDE3BPDE3APTGS2RPS6KA3 | |
| SCHEMBL20888423 | 0.83 | NFE2L2 (0.46) | NFE2L2PDE3BPDE3APTGS2RPS6KA3 | |
| SCHEMBL4567629 | 0.81 | PDE3B (0.48) | PDE3BPDE3AESR1ESR2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123623-A1 | LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2009-11-25 | — | — | EP | disclosed |