Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7856658 | 0.90 | CTDSP1 (0.46) | CTDSP1SMN1; SMN2PLAUPLATCTSL | |
| SCHEMBL7859110 | 0.89 | CTDSP1 (0.44) | CTDSP1SMN1; SMN2PLAUPLATCTSL | |
| SCHEMBL7848750 | 0.81 | MEN1 (0.44) | SMN1; SMN2CTSBCTSSCTSKMEN1 | |
| SCHEMBL7856654 | 0.79 | MEN1 (0.42) | SMN1; SMN2CTSSCTSKMEN1KMT2A | |
| SCHEMBL7848777 | 0.76 | CTSB (0.43) | PLAUPLATCTSLCTSBCTSS | |
| SCHEMBL7858975 | 0.72 | CTDSP1 (0.46) | CTDSP1SMN1; SMN2CTSLCTSBCTSS | |
| SCHEMBL7857675 | 0.71 | LMNA (0.46) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL13222591 | 0.70 | CTDSP1 (0.46) | CTDSP1SMN1; SMN2PLAUPLATCYP3A4 | |
| SCHEMBL7856661 | 0.70 | PKM (0.56) | CTSLCTSBCTSSCTSK | |
| SCHEMBL11937896 | 0.68 | SMN1; SMN2 (0.48) | CTDSP1SMN1; SMN2CYP3A4CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009132453-A1 | CYCLYLAMINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD. (CA) | 2009-11-05 | — | — | WO | disclosed |