Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829825 | 0.89 | TDP1 (0.49) | TDP1MEN1KMT2ACA12CA1 | |
| SCHEMBL9407115 | 0.83 | TDP1 (0.45) | TDP1MEN1KMT2ACA12CA1 | |
| SCHEMBL107781 | 0.81 | HPGD (0.48) | TDP1MEN1KMT2ACA12CA1 | |
| SCHEMBL914851 | 0.79 | POLB (0.47) | TDP1MEN1KMT2ACA12CA1 | |
| SCHEMBL6898817 | 0.79 | TDP1 (0.43) | TDP1MEN1KMT2ACA12CA1 | |
| SCHEMBL23057071 | 0.79 | TDP1 (0.43) | TDP1MEN1KMT2ACA12CA1 | |
| SCHEMBL3364776 | 0.79 | GAA (0.47) | TDP1MEN1KMT2ACA12CA1 | |
| SCHEMBL11140840 | 0.79 | POLB (0.54) | TDP1MEN1KMT2ACA12CA1 | |
| SCHEMBL13637001 | 0.79 | TDP1 (0.43) | TDP1MEN1KMT2ACA12CA1 | |
| SCHEMBL895236 | 0.79 | ALDH1A1 (0.47) | TDP1MEN1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090292135-A1 | ORGANOMETAL BENZENEPHOSPHONATE COUPLING AGENTS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090292135-A1 | ORGANOMETAL BENZENEPHOSPHONATE COUPLING AGENTS | ZNF207, TST, BOLA2; BOLA2B | TDP1 3119/4885MEN1 1650/4885KMT2A 2095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.