Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829825 | 0.89 | TDP1 (0.49) | TDP1MEN1KMT2ACA12CA1 | |
| SCHEMBL9407115 | 0.83 | TDP1 (0.45) | TDP1MEN1KMT2ACA12CA1 | |
| SCHEMBL107781 | 0.81 | HPGD (0.48) | TDP1MEN1KMT2ACA12CA1 | |
| SCHEMBL914851 | 0.79 | POLB (0.47) | TDP1MEN1KMT2ACA12CA1 | |
| SCHEMBL11140840 | 0.79 | POLB (0.54) | TDP1MEN1KMT2ACA12CA1 | |
| SCHEMBL23057071 | 0.79 | TDP1 (0.43) | TDP1MEN1KMT2ACA12CA1 | |
| SCHEMBL3364776 | 0.79 | GAA (0.47) | TDP1MEN1KMT2ACA12CA1 | |
| SCHEMBL13637001 | 0.79 | TDP1 (0.43) | TDP1MEN1KMT2ACA12CA1 | |
| SCHEMBL13636978 | 0.79 | TDP1 (0.43) | TDP1MEN1KMT2ACA12CA1 | |
| SCHEMBL895236 | 0.79 | ALDH1A1 (0.47) | TDP1MEN1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820636-B | Enzyme-responsive cytotoxic polyamino acid, and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2024-05-24 | — | — | CN | disclosed |
| EP-1023044-B1 | APATITE-COATED SOLID COMPOSITION | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-02-04 | — | — | EP | disclosed |
| US-20030185878-A1 | Process for producing phospholipid-containing drug | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1293197-A1 | PROCESS FOR PRODUCING PHOSPHOLIPID-CONTAINING DRUGS | Takeda Chemical Industries, Ltd. (JP) | 2003-03-19 | — | — | EP | disclosed |
| EP-0949927-B1 | PHARMACEUTICAL COMPOSITION CONTAINING OSTEOGENESIS-PROMOTING SUBSTANCE AND A POLYETHYLENE GLYCOL | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-16 | — | — | EP | disclosed |
| EP-1208850-A1 | PASTES WITH THE SUSTAINED RELEASE OF OSTEOGENESIS PROMOTER | Takeda Chemical Industries, Ltd. (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-6344209-B1 | BIODEGRADABLE POLYLACTIC ACID, POLYGLYCOLIC ACID AND COPOLYMERS OF THE TWO FOR BONE DISEASES THERAPY; ANTIBIOTICS, ANTI-INFLAMMATORY AND ANTI-TUMOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-05 | — | — | US | disclosed |
| CN-1321094-A | Bone repair materials/artificial bone compositions | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-07 | — | — | CN | disclosed |
| EP-1120122-A1 | BONE REPAIR MATERIALS/ARTIFICIAL BONE COMPOSITIONS | Takeda Chemical Industries, Ltd. (JP) | 2001-08-01 | — | — | EP | disclosed |
| EP-0460488-B1 | Sulfur-containing heterocyclic compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-07-11 | — | — | EP | disclosed |
| WO-1998015263-A2 | A METHOD FOR PRODUCING A MICROPARTICLE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-04-16 | — | — | WO | disclosed |
| EP-0831808-A1 | OSTEOGENETIC PROMOTING PHARMACEUTICAL COMPOSITION | Takeda Chemical Industries, Ltd. (JP) | 1998-04-01 | — | — | EP | disclosed |
| WO-1998008517-A2 | PHARMACEUTICAL COMPOSITION CONTAINING OSTEOGENESIS-PROMOTING SUBSTANCE AND A POLYETHYLENE GLYCOL | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-05 | — | — | WO | disclosed |
| WO-1996039134-A1 | OSTEOGENETIC PROMOTING PHARMACEUTICAL COMPOSITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-12 | — | — | WO | disclosed |
| CN-1032470-C | Sulfur-containing heterocyclic compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-08-07 | — | — | CN | disclosed |
| EP-0376197-B1 | Sulfur-containing heterocyclic compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-10-12 | — | — | EP | disclosed |
| US-5158943-A | Osteoporosis | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-27 | — | — | US | disclosed |
| EP-0460488-A1 | Sulfur-containing heterocyclic compounds | Takeda Chemical Industries, Ltd. (JP) | 1991-12-11 | — | — | EP | disclosed |
| CN-1045106-A | Sulfur heterocyclic compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1990-09-05 | — | — | CN | disclosed |
| EP-0376197-A1 | Sulfur-containing heterocyclic compounds | Takeda Chemical Industries, Ltd. (JP) | 1990-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030185878-A1 | Process for producing phospholipid-containing drug | PHOSPHO1, PLTP, PTDSS2 | TDP1 2199/4885MEN1 3398/4885KMT2A 2693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.