Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19410334 | 0.90 | LMNA (0.45) | LMNANPC1RAB9AMEN1MAPT | |
| SCHEMBL906924 | 0.86 | CA12 (0.49) | LMNANPC1RAB9AKDM4EMAPT | |
| SCHEMBL18383376 | 0.86 | SMN1; SMN2 (0.47) | LMNANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL25338089 | 0.86 | LMNA (0.46) | LMNANPC1RAB9AGAAMEN1 | |
| SCHEMBL15080278 | 0.84 | CYP3A4 (0.44) | L3MBTL1LMNANPC1RAB9AMEN1 | |
| SCHEMBL12617413 | 0.84 | CYP3A4 (0.44) | L3MBTL1LMNANPC1RAB9AKDM4E | |
| SCHEMBL19393239 | 0.83 | LMNA (0.51) | L3MBTL1LMNANPC1RAB9AGAA | |
| SCHEMBL29575673 | 0.83 | CA2 (0.48) | LMNANPC1RAB9AKDM4ECACNA1H | |
| SCHEMBL26549538 | 0.83 | CA2 (0.48) | LMNANPC1RAB9AKDM4ECACNA1H | |
| SCHEMBL12312858 | 0.82 | CA1 (0.50) | L3MBTL1LMNANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9932365-B2 | Protein labeling with cyanobenzothiazole conjugates | PROMEGA CORPORATION (US) | 2018-04-03 | — | — | US | disclosed |
| US-20170283456-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2017-10-05 | — | — | US | disclosed |
| US-20170283456-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2017-10-05 | — | — | US | disclosed |
| US-9689868-B2 | Protein labeling with cyanobenzothiazole conjugates | PROMEGA CORPORATION (US) | 2017-06-27 | — | — | US | disclosed |
| US-9689868-B2 | Protein labeling with cyanobenzothiazole conjugates | PROMEGA CORPORATION (US) | 2017-06-27 | — | — | US | disclosed |
| EP-3141905-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | Promega Corporation (US) | 2017-03-15 | — | — | EP | disclosed |
| US-20170016888-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2017-01-19 | — | — | US | disclosed |
| US-20170016888-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2017-01-19 | — | — | US | disclosed |
| US-9459249-B2 | Protein labeling with cyanobenzothiazole conjugates | PROMEGA CORPORATION (US) | 2016-10-04 | — | — | US | disclosed |
| US-9459249-B2 | Protein labeling with cyanobenzothiazole conjugates | PROMEGA CORPORATION (US) | 2016-10-04 | — | — | US | disclosed |
| WO-2009142678-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | PROMEGA CORPORATIN (US) | 2009-11-26 | — | — | WO | disclosed |
| US-20090263843-A1 | Protein labeling with cyanobenzothiazole conjugates | PROMEGA CORPORATION (US) | 2009-10-22 | — | — | US | disclosed |
| US-20090263843-A1 | Protein labeling with cyanobenzothiazole conjugates | PROMEGA CORPORATION (US) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090263843-A1 | Protein labeling with cyanobenzothiazole conjugates | QPCTL, BCAT1, QPCT | L3MBTL1 1238/4885LMNA 2607/4885NPC1 1719/4885 |
| US-20170283456-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | QPCTL, BCAT1, QPCT | L3MBTL1 1238/4885LMNA 2607/4885NPC1 1719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.