Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CENPE | Q02224 | 3/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 2/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626813 | 0.89 | CENPE (0.53) | CENPEROCK2ROCK1S1PR1S1PR3 | |
| SCHEMBL13932429 | 0.89 | CENPE (0.49) | CENPEROCK2ROCK1MME | |
| SCHEMBL3462485 | 0.78 | CENPE (0.64) | CENPES1PR1S1PR3S1PR5 | |
| SCHEMBL13162058 | 0.78 | CENPE (0.64) | CENPES1PR1S1PR3S1PR5 | |
| SCHEMBL3461182 | 0.74 | DHODH (0.46) | CENPEROCK2ROCK1TAS1R3TAS1R1 | |
| SCHEMBL13161874 | 0.74 | DHODH (0.46) | CENPEROCK2ROCK1TAS1R3TAS1R1 | |
| SCHEMBL13637353 | 0.73 | CENPE (0.53) | CENPEROCK2ROCK1S1PR1MME | |
| SCHEMBL13161477 | 0.73 | CENPE (0.42) | CENPETAS1R3TAS1R1KCNQ3KCNQ2 | |
| SCHEMBL3462063 | 0.73 | CENPE (0.42) | CENPETAS1R3TAS1R1KCNQ3KCNQ2 | |
| SCHEMBL13637408 | 0.72 | CENPE (0.51) | CENPEROCK2ROCK1S1PR1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286841-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286841-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | KIF5B, KIF2C, PLK1 | CENPE 54/4885ROCK2 685/4885ROCK1 616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.