Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28946119 | 0.83 | GNAI3 (0.37) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL15546025 | 0.82 | PHGDH (0.36) | — | |
| SCHEMBL27269583 | 0.80 | — | — | |
| SCHEMBL13638195 | 0.79 | GNAI3 (0.41) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL3248168 | 0.76 | SLC6A3 (0.41) | — | |
| Hydrochloric Acid SCHEMBL4886955 | 0.74 | GNAI3 (0.42) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL1650151 | 0.74 | SLC6A3 (0.40) | — | |
| SCHEMBL23252498 | 0.73 | GNAI3 (0.36) | GNAI3GNAO1GNAI1DPP4 | |
| SCHEMBL6806038 | 0.72 | KDM4E (0.33) | — | |
| SCHEMBL6944619 | 0.72 | AOC3 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030105098-A1 | 6,9-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines | AVENTISUB II INC. | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105098-A1 | 6,9-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines | CDK6, CDK5, CDK2 | GNAI3 2099/4885GNAO1 2886/4885GNAI1 2256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.